PDGFB-CGO
| 【Numbering】BKME110001 | 【CAS】CAS | ||
| 【Item No.】 | 【specification】 | ||
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Name: PDGFB-CGO
Composition: PDGFB + copper gadolinium oxide
Grain size: 50-200nm
Application: anti-tumor and tumor metastasis
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [main advantages] has super fenton catalytic activity and PT performance, with excellent T1 contrast ability. Significsignificantly improved its tumor-specific delivery, rapidly ablated tumor cells under laser irradiation and promoted PTT. In addition, PDGFB-CGO can rapidly generate rich and highly active Cu (I), catalyzing endogenous hydrogen peroxide (H2O2) into hydroxyl radical (OH), achieving ultra-high anti-cancer CDT efficiency. The influx of Cu (I) breaks copper homeostasis to inhibiting epithelial-to-mesenchymal transition (EMT) and tumor angiogenesis. This process limits cell migration and invasion, thus greatly preventing cancer metastasis.
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Composition: PDGFB + copper gadolinium oxide
Grain size: 50-200nm
Application: anti-tumor and tumor metastasis
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [main advantages] has super fenton catalytic activity and PT performance, with excellent T1 contrast ability. Significsignificantly improved its tumor-specific delivery, rapidly ablated tumor cells under laser irradiation and promoted PTT. In addition, PDGFB-CGO can rapidly generate rich and highly active Cu (I), catalyzing endogenous hydrogen peroxide (H2O2) into hydroxyl radical (OH), achieving ultra-high anti-cancer CDT efficiency. The influx of Cu (I) breaks copper homeostasis to inhibiting epithelial-to-mesenchymal transition (EMT) and tumor angiogenesis. This process limits cell migration and invasion, thus greatly preventing cancer metastasis.
Title:PDGF receptor-β-targeted copper-gadolinium-oxide self-assembled nanoclusters suppress tumor growth and metastasis via copper overload-mediated apoptosis and anti-angiogenesis
Article link:https://doi.org/10.1016/j.cej.2022.141227| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance.The website pictures are from the Internet. The pictures are for reference only. Please take the real object as the standard. In case of infringement, please contact us to delete them immediately. |
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